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In a patient who feels better on vitamin B12 injections despite normal serum B12 levels and has a 5,10‑methylenetetrahydrofolate reductase (MTHFR) deficiency, should the B12 therapy be continued?
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Some patients, particularly those with neurological involvement, may benefit from more frequent dosing (every 2 months rather than 3 months), but this should be medically supervised rather than self-adjusted
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