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Renal stress and peripheral nerve damage are also possible side effects

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The variants associated with the combined PDFF and NAFL at genome-wide significance (GWS) were nominally significant for both phenotypes ( P 0.19) are a splice-region variant in HSD17B13 , rs72613567[TA], which has been reported as being associated with NASH 21 , and a missense variant p.Glu366Lys in SERPINA1 , which causes α 1 -antitrypsin deficiency 36