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Factors that shape the decision: Type of anxiety disorder (GAD, panic disorder, social anxiety, etc.) Severity and how long symptoms have persisted How you've responded to treatments in the past Other medications you're currently taking Existing medical conditions, including heart, liver, or kidney issues Potential side effects you're most concerned about Risk tolerance around dependence, especially relevant for benzodiazepines Age and overall health circumstances Pregnancy or breastfeeding status, since some medications carry more risk than others Cost, insurance coverage, and medication availability For anxiety that hasn't responded to standard SSRIs, SNRIs, or therapy, some clinicians may discuss additional options like ketamine-assisted therapy