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ER stress is related to cellular ROS generation and altered redox balance during early INH exposure To investigate if mitochondrial ROS is the critical factor impairing mitochondrial function and causing cellular oxidative stress, cellular ROS was monitored using cellROX and mitochondrial ROS using mitoSOX from 12 to 72 h after INH treatment

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The GSTT*0 phenotype varies between ethnic groups and is found to be highest in Chinese (65%) and lowest in Mexican American (9%) populations [55]