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60 Thus, 100 ng/ml of insulin increased proliferation rates of human breast, colon, prostate and bladder cancer cell lines in a glucose-dependent manner, achieving 7–44% higher proliferation when combined with diabetogenic glucose concentrations of 11 mm compared with glucose concentrations of 5.5 mm without added insulin
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CUMS enhanced DNA methylation at specific CpG sites on the glial cell line-derived neurotrophic factor ( GDNF ) promoter of BALB mice
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